BDBM50299569 3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6-dimethylmorpholin-4-yl)-2-oxoethyl]oxime::CHEMBL570803

SMILES COc1ccc(\C=N\OCC(=O)N2CC(C)OC(C)C2)cc1OC1CCCC1

InChI Key InChIKey=JEXHQZPMUKFOIV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50299569   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of recombinant human PDE4D3 expressed in baculoviral systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human recombinant PDE4D3 expressed in baculovirus system by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant PDE4D expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D catalytic domain (244 to 578 residues) expressed in Escherichia coli BL21(DE3) pLysS cells assessed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50299569(3-(cyclopentyloxy)-4-methoxybenzaldehyde O-[2-(2,6...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of C-terminal 6His-tagged human PDE4D3 expressed in baculovirus infected Sf9 insect cells assessed as reduction in 5'-AMP formation using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed