BDBM50299491 CHEMBL583403::[4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid,(3S)-3-morpholinylmethyl ester

SMILES CCC1=C2C(N=C1NC(=O)OC[C@@H]1COCCN1)N=CN=C2Nc1ccc2n(Cc3cccc(F)c3)ncc2c1

InChI Key InChIKey=IWUDGWPMXMXFFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299491   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50299491([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50299491([4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamin...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed