BDBM50299489 CHEMBL567197::{4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl}-carbamic acid cis-4-amino-4-methylcyclohexyl ester

SMILES CCC1=C2C(N=C1NC(=O)O[C@H]1CC[C@@](C)(N)CC1)N=CN=C2Nc1ccc2n(Cc3ccccc3)ncc2c1

InChI Key InChIKey=HVJQYIDZJSEHCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299489   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50299489({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant HER2 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50299489({4-(1-Benzyl-1H-indazol-5-ylamino)-5-ethyl-pyrrolo...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant HER1 expressed in Sf9 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed