BDBM50299457 CHEMBL575093::{7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}acetonitrile

SMILES Clc1cccc(COc2ccc3c(CC#N)cc(=O)oc3c2)c1

InChI Key InChIKey=GJOXPEUFUOYRAD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50299457   

TargetAmine oxidase [flavin-containing] B(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50299457({7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}ace...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B in brain mitochondrial homogenate assessed as 4-hydroxyquinoline by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50299457({7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}ace...)
Affinity DataIC50: 16nMAssay Description:Inhibition of MAO-B from Wistar rat brain by radioenzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50299457({7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}ace...)
Affinity DataIC50: 470nMAssay Description:Inhibition of MAO-A from Wistar rat brain by radioenzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50299457({7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}ace...)
Affinity DataIC50: 16nMAssay Description:Inhibition of Sprague-Dawley rat MAO-B using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50299457({7-[(3-Chlorobenzyl)oxy]-2-oxo-2H-chromen-4-yl}ace...)
Affinity DataIC50: 468nMAssay Description:Inhibition of Sprague-Dawley rat MAO-A using Kynuramine as substrate assessed as formation of 4-hydroxyquinoline preincubated for 5 mins prior to sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed