BDBM50299412 4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-triazole-1,4-diyl)]bis(N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide)::CHEMBL574534

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2cn(Cc3ccc(cc3)-c3ccc(Cn4cc(nn4)-c4ccc(cc4)C(=O)NCCCCN4CCN(CC4)c4ccccc4OC)cc3)nn2)CC1

InChI Key InChIKey=KEOJOHYWCQCCER-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50299412   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50299412(4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-tri...)
Affinity DataKi:  70nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50299412(4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-tri...)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50299412(4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-tri...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]ketanserin from 5HT2 receptor in pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50299412(4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-tri...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D2long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50299412(4,4'-[Biphenyl-4,4'-diylbis(methylene-1H-1,2,3-tri...)
Affinity DataKi:  9.50E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed