BDBM50299359 CHEMBL575797::N-(cyclopropylmethyl)-1-(2-(1-(2,4-dimethoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)ethylsulfonyl)piperidin-4-amine

SMILES COc1ccc(c(OC)c1)S(=O)(=O)N1C(CCS(=O)(=O)N2CCC(CC2)NCC2CC2)CCc2ccccc12

InChI Key InChIKey=JZKUQQJGKRTKRL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299359   

TargetVasopressin V1b receptor(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299359(N-(cyclopropylmethyl)-1-(2-(1-(2,4-dimethoxyphenyl...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299359(N-(cyclopropylmethyl)-1-(2-(1-(2,4-dimethoxyphenyl...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299359(N-(cyclopropylmethyl)-1-(2-(1-(2,4-dimethoxyphenyl...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1a receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed