BDBM50299357 1-(2-(1-(2,4-dimethoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)ethylsulfonyl)-N-propylpiperidin-4-amine::CHEMBL575987

SMILES CCCNC1CCN(CC1)S(=O)(=O)CCC1CCc2ccccc2N1S(=O)(=O)c1ccc(OC)cc1OC

InChI Key InChIKey=XPPJMZLNLXTIMY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50299357   

TargetVasopressin V1b receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299357(1-(2-(1-(2,4-dimethoxyphenylsulfonyl)-1,2,3,4-tetr...)
Affinity DataKi:  152nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299357(1-(2-(1-(2,4-dimethoxyphenylsulfonyl)-1,2,3,4-tetr...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]Arg8-vasopressin from rat vasopressin V1b receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50299357(1-(2-(1-(2,4-dimethoxyphenylsulfonyl)-1,2,3,4-tetr...)
Affinity DataKi:  1.27E+3nMAssay Description:Displacement of [3H]Arg8-vasopressin from human vasopressin V1a receptor expressed in CHO-K1 cells by Packard Topcount scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed