BDBM50299174 (6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-7,9(4H)-dicarboxamide::CHEMBL584356

SMILES CCN(CC)C(=O)[C@H]1CN([C@@H]2Cc3c[nH]c4cccc(C2=C1)c34)C(=O)Nc1cccc(C)c1

InChI Key InChIKey=XQFSXHZCPXWBLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299174   

TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299174((6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human CXCR3 expressed in L1.2 cells assessed as inhibition of I-TAC-induced Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299174((6aR,9R)-N9,N9-diethyl-N7-m-tolyl-6,6a,8,9-tetrahy...)
Affinity DataIC50: 231nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed