BDBM50299166 (6aR,9R)-N,N-diethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide::4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide::CHEMBL21343

SMILES CCN(CC)C(=O)[C@H]1CN[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34

InChI Key InChIKey=SUXLVXOMPKZBOV-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50299166   

TargetAlpha-2C adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 143nMAssay Description:Inhibition of 5HT7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 16nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 54nMAssay Description:Inhibition of 5HT2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]I-TAC from human CXCR3 expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50299166(4,6,6a,7,8,9-Hexahydro-indolo[4,3-fg]quinoline-9-c...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed