BDBM50299068 CHEMBL575895::N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide

SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO

InChI Key InChIKey=QPFIKHZWPMXTRS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299068   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50299068(N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed