BDBM50298829 (S)-5-(3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-ynyl)-6-methylpyrimidine-2,4-diamine::5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine::CHEMBL576976

SMILES COc1cc(cc(c1)-c1c(C)cccc1C)[C@H](C)C#Cc1c(C)nc(N)nc1N

InChI Key InChIKey=XZXVRKHUCSXVBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298829   

TargetDihydrofolate reductase(Yeast)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50298829(5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)b...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed