BDBM50298793 (rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-yl)propyl)-1H-1,2,3-triazol-4-yl)butyl)-1-m-tolyl-2,3,4,5-tetrahydro-1Hbenzo[d]azepine-7,8-diol::CHEMBL582945

SMILES COc1ccccc1N1CCN(CCCn2cc(CCCCN3CCc4cc(O)c(O)cc4C(C3)c3cccc(C)c3)nn2)CC1

InChI Key InChIKey=JQGRSOUGXXQUQI-UHFFFAOYSA-N

Data  3 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298793   

TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataIC50: 3.27E+4nMAssay Description:Antagonist activity at dopamine D1 receptor expressed in HEK293 cells by by [35S]GTPgammaS binding assay in presence of SKF-38393More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at dopamine D2 receptor expressed in HEK293 cells by by [35S]GTPgammaS binding assay in presence of quinpiroleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at 5HT1A receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  133nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50298793((rac)-3-(4-(1-(3-(4-(2-Methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed