BDBM50298190 (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-2-isopropyl-6-(isopropyl(4-methoxy-3-(3-methoxypropoxy)benzyl)amino)hexanamide::CHEMBL560486

SMILES COCCCOc1cc(CN(C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)ccc1OC

InChI Key InChIKey=GKGIFKZUIBKKDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298190   

TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298190((2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetRenin(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298190((2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopr...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetRenin(Rat)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298190((2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopr...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of rat reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCathepsin D(Bovine)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298190((2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed