BDBM50298152 (4S)5-[4-(Butoxycarbonyl)iperazin-1-yl]-4-({[4-(2-hydroxyethoxy)6-phenylpyridin-2-yl]carbonyl}amino)5-oxopentanoic Acid::(S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(2-hydroxyethoxy)-6-phenylpicolinamido)-5-oxopentanoic acid::CHEMBL562405

SMILES CCCCOC(=O)N1CCN(CC1)C(=O)[C@H](CCC(O)=O)NC(=O)c1cc(OCCO)cc(n1)-c1ccccc1

InChI Key InChIKey=XIKWULOIMQVWSR-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298152   

TargetP2Y purinoceptor 12(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50298152((S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(2-h...)
Affinity DataIC50: 7.80E+3nMAssay Description:Antagonist activity at human P2Y12 receptor assessed as inhibition of ADP-induced platelet-rich plasma aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50298152((S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(2-h...)
Affinity DataKi:  20nMAssay Description:Displacement of [33P]ADP from human recombinant P2Y12 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50298152((S)-5-(4-(butoxycarbonyl)piperazin-1-yl)-4-(4-(2-h...)
Affinity DataKi:  21nMAssay Description:Binding affinity to human recombinant P2Y12 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed