BDBM50298109 3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-butyrylamino)-propionic acid::CHEMBL551622

SMILES OC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CC(S)C(F)(F)F

InChI Key InChIKey=JHEKOWDFMNIEBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298109   

TargetAngiotensin-converting enzyme(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetNeprilysin [1-24](Pig)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50: 580nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298109(3-(1H-Indol-3-yl)-2-(4,4,4-trifluoro-3-mercapto-bu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed