BDBM50298106 3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)propanoic acid::CHEMBL560685

SMILES OC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)F

InChI Key InChIKey=AGHTYLMQJBOVQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298106   

TargetAngiotensin-converting enzyme(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant ACE by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetNeprilysin [1-24](Pig)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50: 300nMAssay Description:Inhibition of pig kidney NEP by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
Dipartimento Di Chimica

Curated by ChEMBL
LigandPNGBDBM50298106(3-phenyl-2-(4,4,4-trifluoro-3-mercaptobutanamido)p...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant ECE1 by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed