BDBM50298097 CHEMBL558535::N4-((2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)butan-2-yl)-N6-butylpyrimidine-4,6-diamine

SMILES CCCCNc1cc(N[C@@H](C)[C@@H](Cc2ccc(Cl)cc2)c2cccc(Br)c2)ncn1

InChI Key InChIKey=WFJFNLUJCRIUNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298097   

TargetCannabinoid receptor 2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50298097(N4-((2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)bu...)
Affinity DataIC50: 2.96E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from human recombinant CB2 receptor expressed in CHOK1 cells by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50298097(N4-((2S,3S)-3-(3-bromophenyl)-4-(4-chlorophenyl)bu...)
Affinity DataIC50: 16.3nMAssay Description:Displacement of [3H]CP-55940 from cannabinoid CB1 receptor in Sprague-Dawley rat cerebellar membrane by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed