BDBM50298032 (S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)pyrrolidin-3-yl)amino)benzonitrile::CHEMBL539731

SMILES Clc1ccccc1CN([C@H]1CCN(CC#N)C1)c1ccc(C#N)c(Cl)c1

InChI Key InChIKey=AQDBHWCJEXNMMR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50298032   

TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataIC50: 8nMAssay Description:Binding affinity to PR by fluorescence polarization based competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50298032((S)-2-chloro-4-((2-chlorobenzyl)(1-(cyanomethyl)py...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at PR expressed in african green monkey CV-1 cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed