BDBM50297999 (+/-)-5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid::5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide::5-(2,5-difluorophenyl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrochloride::CHEMBL1237148::CHEMBL542000

SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cc(F)ccc1F

InChI Key InChIKey=UPIXPUKUUGSFKW-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50297999   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50297999(CHEMBL542000 | 5-(2,5-difluorophenyl)-4,5,6,7-tetr...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed