BDBM50297922 3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benzenesulfonamide::CHEMBL551889

SMILES Clc1cccc(c1)S(=O)(=O)NCc1ccc(cc1)C(=O)N1CCCC1

InChI Key InChIKey=ZGDLYYSRXDDQDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297922   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50297922(3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benze...)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50297922(3-Chloro-N-[4-(pyrrolidine-1-carbonyl)benzyl]benze...)
Affinity DataIC50: 480nMAssay Description:Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed