BDBM50297915 4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-carbonyl]benzyl}benzenesulfonmide::CHEMBL556657

SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=NGRDCHBJZRZZLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297915   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50297915(4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50297915(4-Chloro-N-{4-[(2R,6S)-2,6-dimethylmorpholine-4-ca...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed