BDBM50297519 (+/-)-1,2-Bis-(4-hydroxy-phenyl)-propane::4,4'-(propane-1,2-diyl)diphenol::CHEMBL554507

SMILES CC(Cc1ccc(O)cc1)c1ccc(O)cc1

InChI Key InChIKey=JISNDAMZBNGEAC-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297519   

TargetEstrogen receptor beta(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50297519(4,4'-(propane-1,2-diyl)diphenol | (+/-)-1,2-Bis-(4...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at ERbeta expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50297519(4,4'-(propane-1,2-diyl)diphenol | (+/-)-1,2-Bis-(4...)
Affinity DataEC50:  1.20nMAssay Description:Activity at human ERbeta expressed in HEC1 cells co-transfected with 2ERE-pS2-Luc assessed as relative transcriptional potency by luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50297519(4,4'-(propane-1,2-diyl)diphenol | (+/-)-1,2-Bis-(4...)
Affinity DataEC50:  6.5nMAssay Description:Activity at human ERalpha expressed in HEC1 cells co-transfected with 2ERE-pS2-Luc assessed as relative transcriptional potency by luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50297519(4,4'-(propane-1,2-diyl)diphenol | (+/-)-1,2-Bis-(4...)
Affinity DataEC50:  6.5nMAssay Description:Agonist activity at ERalpha expressed in human HEC1 cells assessed as transcriptional potency after 24 hrs by luciferase-beta galactosidase reporter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed