BDBM50297506 CHEMBL551074::l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((methylsulfonyl)oxy)-4,5alpha-epoxymorphinan

SMILES CS(=O)(=O)O[C@@H]1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC1CC1)c45

InChI Key InChIKey=LRMIBIGOYIYIOH-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50297506   

TargetMu-type opioid receptor(Human)
University of New England

Curated by ChEMBL
LigandPNGBDBM50297506(l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((meth...)
Affinity DataEC50:  2.60nMAssay Description:Inverse agonist activity at human recombinant mu opioid receptor expressed in CHO cells after 3 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of New England

Curated by ChEMBL
LigandPNGBDBM50297506(l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((meth...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of New England

Curated by ChEMBL
LigandPNGBDBM50297506(l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((meth...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of New England

Curated by ChEMBL
LigandPNGBDBM50297506(l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((meth...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of New England

Curated by ChEMBL
LigandPNGBDBM50297506(l7-(cyclopropylmethyl)-3,l4-dihydroxy-6beta-((meth...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed