BDBM50297480 (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime::1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-phenylindolin-2-one::CHEMBL549385

SMILES c1ccc(cc1)c2cccc3c2/C(=N/O)/C(=O)N3Cc4cc(cc5c4OCOC5)F

InChI Key InChIKey=SZYREAUDQRVVLV-UHFFFAOYSA-N

Data  3 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297480   

TargetMitogen-activated protein kinase 10(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297480(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297480(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  9.50E+3nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297480(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of ERK2 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed