BDBM50297461 (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-[(E)-2-phenylethenyl]-1H-indole-2,3-dione 3-oxime::1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3-(hydroxyimino)-4-styrylindolin-2-one::CHEMBL561540

SMILES c1ccc(cc1)C=Cc2cccc3c2/C(=N/O)/C(=O)N3Cc4cc(cc5c4OCOC5)F

InChI Key InChIKey=DDHASJXGNUWZTM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297461   

TargetMitogen-activated protein kinase 14(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297461(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  230nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297461(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-3...)
Affinity DataKi:  740nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed