BDBM50297415 CHEMBL564893::N-[3,3-Bis-(4-fluorophenyl)-propyl]-2-(2,2,2-trifluoro-ethoxy)-isonicotinamide

SMILES Fc1ccc(cc1)C(CCNC(=O)c1ccnc(OCC(F)(F)F)c1)c1ccc(F)cc1

InChI Key InChIKey=GAXUBAFERADYKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297415   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297415(N-[3,3-Bis-(4-fluorophenyl)-propyl]-2-(2,2,2-trifl...)
Affinity DataIC50: 5nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297415(N-[3,3-Bis-(4-fluorophenyl)-propyl]-2-(2,2,2-trifl...)
Affinity DataIC50: 7nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed