BDBM50297399 CHEMBL564145::N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)-propyl]-nicotinamide

SMILES CS(=O)(=O)c1ccc(cc1)C(CCNC(=O)c1cccnc1)c1ccc(F)cc1

InChI Key InChIKey=BSODTIJQLXXISQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297399   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataIC50: 8nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataIC50: 14nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297399(N-[3-(4-Fluorophenyl)-3-(4-methanesulfonyl-phenyl)...)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed