BDBM50297398 CHEMBL563216::N-[3,3-Bis-(4-fluorophenyl)-propyl]-nicotinamide

SMILES Fc1ccc(cc1)C(CCNC(=O)c1cccnc1)c1ccc(F)cc1

InChI Key InChIKey=PGLSPMQRWMIFOQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297398   

TargetBifunctional epoxide hydrolase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297398(N-[3,3-Bis-(4-fluorophenyl)-propyl]-nicotinamide |...)
Affinity DataIC50: 8nMAssay Description:Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Rat)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297398(N-[3,3-Bis-(4-fluorophenyl)-propyl]-nicotinamide |...)
Affinity DataIC50: 7nMAssay Description:Displacement of rhodamine-labeled probe from rat soluble epoxide hydrolase by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed