BDBM50297392 CHEMBL560141::ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate

SMILES CCOC(=O)CC1C(C(=O)OCC)C(=N)Oc2ccc(cc12)-c1ccccc1

InChI Key InChIKey=VPTYYCNWZYPMQH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297392   

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM50297392(ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297392(ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-...)
Affinity DataKi:  3.44E+5nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed