BDBM50297361 1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropyl]-3-isopropyl-1,3-dihydro-2H-benzimidazol-2-one::CHEMBL563518

SMILES CNC[C@@H](O)[C@H](c1ccccc1)n1c2ccccc2n(C(C)C)c1=O

InChI Key InChIKey=GISYFCKSYSNKHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297361   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297361(1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...)
Affinity DataIC50: 13.4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in MDCK-Net6 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50297361(1-[(1S,2R)-2-Hydroxy-3-(methylamino)-1-phenylpropy...)
Affinity DataIC50: 10.8nMAssay Description:Inhibition of [3H]nisoxetine binding to human NET expressed in MDCK-Net6 cells by plate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed