BDBM50297283 5-Methyl-3-[2-(5-methyl-3a,7a-dihydro-indol-1-yl)-ethyl]-1H-indole::CHEMBL560278

SMILES Cc1ccc2n(CCc3c[nH]c4ccc(C)cc34)ccc2c1

InChI Key InChIKey=DGMFAHKJFBFNKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297283   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50297283(5-Methyl-3-[2-(5-methyl-3a,7a-dihydro-indol-1-yl)-...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50297283(5-Methyl-3-[2-(5-methyl-3a,7a-dihydro-indol-1-yl)-...)
Affinity DataIC50: 9.60E+5nMAssay Description:Inhibition of human CDK2/ Cyclin A catalytic subunit expressed in Sf9 insect cells assessed as histone H1 phosphorylation-associated depletion in ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed