BDBM50297192 CHEMBL560135::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-(4-phenoxycyclohexylidene)acetamide

SMILES Fc1ccc2cc(CN3CC[C@H](C3)NC(=O)C=C3CCC(CC3)Oc3ccccc3)ccc2c1

InChI Key InChIKey=BLIXSIRUUZYDMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297192   

TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50297192(N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-...)
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed