BDBM50297179 CHEMBL562923::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(4-hydroxybenzoyl)piperidin-4-ylidene]acetamide

SMILES [#8]-c1ccc(cc1)-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]-c2ccc3cc(F)ccc3c2)-[#6]-1

InChI Key InChIKey=ATAMULBOORAYEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297179   

TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50297179(N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-...)
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed