BDBM50297175 CHEMBL562922::N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-3-yl}-2-[1-(2-hydroxy-6-methoxybenzoyl)piperidin-4-ylidene]-acetamide

SMILES [#6]-[#8]-c1cccc(-[#8])c1-[#6](=O)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]/[#6](=O)-[#7]-[#6@@H]-1-[#6]-[#6]-[#7](-[#6]-c2ccc3cc(F)ccc3c2)-[#6]-1

InChI Key InChIKey=JCMDVXYINIWZHU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297175   

TargetC-C chemokine receptor type 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50297175(N-{(3R)-1-[(6-Fluoro-2-naphthyl)methyl]pyrrolidin-...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human CCR3 expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed