BDBM50297150 3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a]azulen-9-one::CHEMBL571897

SMILES COc1ccc2sc3c(CCCNC3=O)c2c1

InChI Key InChIKey=BZQVWTDKMSTNBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297150   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297150(3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a...)
Affinity DataIC50: 500nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297150(3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a...)
Affinity DataIC50: 360nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297150(3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed