BDBM50297143 (R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL541448

SMILES COc1cccc(COc2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)c1

InChI Key InChIKey=URPBNNONUNUVHW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297143   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297143((R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetra...)
Affinity DataIC50: 110nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297143((R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetra...)
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297143((R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetra...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed