BDBM50297137 (R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL560737

SMILES CCCNC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1

InChI Key InChIKey=FHYKOYKLHAIARC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297137   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297137((R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 450nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297137((R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297137((R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of MK2 in human U937 cells assessed as blockade of LPS-stimulated TNFalpha productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed