BDBM50297101 (S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(trifluoromethyl)benzamide::CHEMBL559802

SMILES FC(F)(F)c1ccccc1C(=O)N(CC1CC1)[C@H]1CCNC1

InChI Key InChIKey=NQUQUDJZIDCEFJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50297101   

LigandPNGBDBM50297101((S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(t...)
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
LigandPNGBDBM50297101((S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(t...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human recombinant NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297101((S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(t...)
Affinity DataKi:  581nMAssay Description:Displacement of [3H]citalopram from human recombinant SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50297101((S)-N-(cyclopropylmethyl)-N-(pyrrolidin-3-yl)-2-(t...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human recombinant DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed