BDBM50296879 (4,4-diphenylpiperidin-1-yl)((1R,4R)-4-((R)-1-(4-methoxyphenyl)ethylamino)-2,2-dimethylcyclohexyl)methanone::CHEMBL549851

SMILES COc1ccc(cc1)[C@@H](C)N[C@@H]1CC[C@@H](C(=O)N2CCC(CC2)(c2ccccc2)c2ccccc2)C(C)(C)C1

InChI Key InChIKey=PBANDLYPUDAWHY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296879   

TargetSodium-dependent serotonin transporter(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296879((4,4-diphenylpiperidin-1-yl)((1R,4R)-4-((R)-1-(4-m...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]imipramine from human serotonin transporter expressed in CHO cell membrane by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296879((4,4-diphenylpiperidin-1-yl)((1R,4R)-4-((R)-1-(4-m...)
Affinity DataIC50: 530nMAssay Description:Displacement of [35S]MK499 from human ERG potassium channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296879((4,4-diphenylpiperidin-1-yl)((1R,4R)-4-((R)-1-(4-m...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [125I]PYY from human recombinant neuropeptide Y1 receptor expressed in CHO (NFAT-bla) cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed