BDBM50296748 CHEMBL564850::naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate

SMILES O=C(Oc1ccc2ccccc2c1)N1CCN2CCC1CC2

InChI Key InChIKey=MQZFLDZRBIKMGM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296748   

LigandPNGBDBM50296748(naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-ca...)
Affinity DataIC50: 4.91E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50296748(naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-ca...)
Affinity DataIC50: 3.16E+3nMAssay Description:Displacement of [3H]LY278584 from human 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50296748(naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-ca...)
Affinity DataIC50: 9.88E+3nMAssay Description:Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50296748(naphthalen-2-yl 1,4-diazabicyclo[3.2.2]nonane-4-ca...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed