BDBM50296746 4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate::CHEMBL555703

SMILES Fc1cc(OC(=O)N2CCN3CCC2CC3)ccc1Cl

InChI Key InChIKey=HKCDBLXAWUUUQZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296746   

LigandPNGBDBM50296746(4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]non...)
Affinity DataIC50: 9.96E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50296746(4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]non...)
Affinity DataIC50: 6.98E+3nMAssay Description:Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
LigandPNGBDBM50296746(4-chloro-3-fluorophenyl 1,4-diazabicyclo[3.2.2]non...)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed