BDBM50296646 CHEMBL557515::N-tert-butyl-3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-ylamino)-4-methylbenzamide

SMILES Cc1ccc(cc1Nc1cc(=O)n(C)c2n(ncc12)-c1ccc(F)cc1F)C(=O)NC(C)(C)C

InChI Key InChIKey=YNELBTNTUVNEMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296646   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50296646(N-tert-butyl-3-(1-(2,4-difluorophenyl)-7-methyl-6-...)
Affinity DataIC50: 269nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed