BDBM50296583 (1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3-yl)-4-methyl-1H-pyrazol-3-yl)methyl)cyclopentanamine::CHEMBL557653

SMILES Cc1c(CN[C@H]2CC[C@@H](F)C2)[nH]nc1-c1cnc(C)c(F)c1

InChI Key InChIKey=HGMBWWNKONNNTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296583   

TargetNociceptin receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296583((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296583((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)
Affinity DataIC50: 9.90nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed