BDBM50296239 (2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,5-dihydroxy-4-methoxybenzoate::CHEMBL551313

SMILES COc1c(O)cc(cc1O)C(=O)O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c1cc(O)c(O)c(O)c1

InChI Key InChIKey=BMJHAAZDURGGSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296239   

TargetMatrix metalloproteinase-14(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human recombinant MT1-MMP expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrilysin(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant MMP7 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Shizuoka and Global Coe Program

Curated by ChEMBL
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant MMP2 expressed in Escherichia coli by fluorogenic peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50296239((2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)ch...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of DYRK1A (unknown origin) using HT-497 as substrate preincubated with compound followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed