BDBM50296188 CHEMBL558248::trans-1-{3-[4-(3-Methyl-4,4-dioxo-3,4-dihydro-2H-4lambda*6*-benzo[1,4]oxathiin-2-yl)-phenoxy]-propyl}-pyrrolidine

SMILES C[C@@H]1[C@H](Oc2ccccc2S1(=O)=O)c1ccc(OCCCN2CCCC2)cc1

InChI Key InChIKey=ITYMMRKSCDTSQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296188   

TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296188(trans-1-{3-[4-(3-Methyl-4,4-dioxo-3,4-dihydro-2H-4...)
Affinity DataIC50: 0.600nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS binding by ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296188(trans-1-{3-[4-(3-Methyl-4,4-dioxo-3,4-dihydro-2H-4...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of [35S]MK499 binding to human ERG transfected in HEK293 cells by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed