BDBM50296184 CHEMBL564514::cis-1-(3-(4-(3-phenyl-2,3-dihydrobenzo[b][1,4]oxathiin-2-yl)phenoxy)propyl)pyrrolidine

SMILES C(COc1ccc(cc1)[C@H]1Oc2ccccc2S[C@H]1c1ccccc1)CN1CCCC1

InChI Key InChIKey=RIDRYHZYVUEBMC-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50296184   

TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296184(cis-1-(3-(4-(3-phenyl-2,3-dihydrobenzo[b][1,4]oxat...)
Affinity DataIC50: 3nMAssay Description:Inverse agonist activity at human cloned histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS binding by ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296184(cis-1-(3-(4-(3-phenyl-2,3-dihydrobenzo[b][1,4]oxat...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [35S]MK499 binding to human ERG transfected in HEK293 cells by microscintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296184(cis-1-(3-(4-(3-phenyl-2,3-dihydrobenzo[b][1,4]oxat...)
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296184(cis-1-(3-(4-(3-phenyl-2,3-dihydrobenzo[b][1,4]oxat...)
Affinity DataKi:  3nMAssay Description:Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed