BDBM50296153 CHEMBL550514::N-(2-(4-(4-fluorophenyl)pyrrolo[1,2-a]quinoxalin-5(4H)-yl)-2-oxoethyl)-N-isopropyl-3,3-dimethylbutanamide

SMILES CC(C)N(CC(=O)N1C(c2cccn2-c2ccccc12)c1ccc(F)cc1)C(=O)CC(C)(C)C

InChI Key InChIKey=JZFTULYYOXZLRD-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296153   

TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296153(N-(2-(4-(4-fluorophenyl)pyrrolo[1,2-a]quinoxalin-5...)
Affinity DataEC50:  1.10E+3nMAssay Description:Inverse agonist activity at human CB1 receptor by [35S]GTPgammaS incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296153(N-(2-(4-(4-fluorophenyl)pyrrolo[1,2-a]quinoxalin-5...)
Affinity DataKi:  1.03E+3nMAssay Description:Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed