BDBM50296147 3-tert-butyl-1-isopropyl-1-(2-(4-(4-methoxyphenyl)pyrrolo[1,2-a]quinoxalin-5(4H)-yl)-2-oxoethyl)urea::CHEMBL565190

SMILES COc1ccc(cc1)C1N(C(=O)CN(C(C)C)C(=O)NC(C)(C)C)c2ccccc2-n2cccc12

InChI Key InChIKey=VNBSZADQGVZUID-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296147   

TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296147(3-tert-butyl-1-isopropyl-1-(2-(4-(4-methoxyphenyl)...)
Affinity DataEC50:  1.50E+3nMAssay Description:Inverse agonist activity at human CB1 receptor by [35S]GTPgammaS incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296147(3-tert-butyl-1-isopropyl-1-(2-(4-(4-methoxyphenyl)...)
Affinity DataKi:  308nMAssay Description:Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296147(3-tert-butyl-1-isopropyl-1-(2-(4-(4-methoxyphenyl)...)
Affinity DataKi:  4.95E+3nMAssay Description:Displacement of [3H]rimonabant from human CB2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed