BDBM50296142 1-(1-(4-chlorophenyl)-4-(3-methoxyphenyl)-5-(4-morpholinophenyl)-4,5-dihydro-1H-1,2,4-triazol-3-yl)ethanone::CHEMBL554943

SMILES COc1cccc(c1)N1C(N(N=C1C(C)=O)c1ccc(Cl)cc1)c1ccc(cc1)N1CCOCC1

InChI Key InChIKey=AYULBOXVHKIVEG-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296142   

TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296142(1-(1-(4-chlorophenyl)-4-(3-methoxyphenyl)-5-(4-mor...)
Affinity DataEC50:  600nMAssay Description:Inverse agonist activity at human CB1 receptor by [35S]GTPgammaS incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296142(1-(1-(4-chlorophenyl)-4-(3-methoxyphenyl)-5-(4-mor...)
Affinity DataKi:  227nMAssay Description:Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50296142(1-(1-(4-chlorophenyl)-4-(3-methoxyphenyl)-5-(4-mor...)
Affinity DataKi:  3.92E+3nMAssay Description:Displacement of [3H]rimonabant from human CB2 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed