BDBM50296118 2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amino)hexylamino)cyclohexa-2,5-diene-1,4-dione::CHEMBL556581

SMILES CCN(CCCCCCNc1cc(O)c(cc1O)N=CCCCCCN(CC)[C@@H](C)c1ccccc1OC)[C@@H](C)c1ccccc1OC

InChI Key InChIKey=KVSCLGVPFHLSOB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296118   

TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 7.91E+3nMAssay Description:Inhibition of human AChE-induced amyloid beta (1-40) aggregation by thioflavin T fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 958nMAssay Description:Inhibition of human recombinant BchE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum-Bologna University

Curated by ChEMBL
LigandPNGBDBM50296118(2,5-bis(6-(ethyl((S)-1-(2-methoxyphenyl)ethyl)amin...)
Affinity DataIC50: 4.03nMAssay Description:Inhibition of human recombinant AChE preincubated 20 mins before substrate addition by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed